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Magnesium Malate

4.8
★ ★ ★ ★ ★
(21984 ratings)
Magnesium 425 mg
Product Image
Score79
A transparent, economical magnesium malate formula offers good absorption, with high dose and tablet burden as the main compromises.
How scoring works
Quantity:180 Tablet(s) • (60 servings)
Goals:
General Health
Stress Relief
Heart Health
Energy
Cardiovascular Support
Bone Health
Testosterone Support
Digestive Health

Score 79

A transparent, economical magnesium malate formula offers good absorption, with high dose and tablet burden as the main compromises.
How scoring works

Also available as

1 option
360 servings Magnesium 425 mg • 360 Tablet(s) • 120 servings $29.38 ($0.24 per serving)
$14.98($0.24 per serving)
iHerb
$ 18.55
Vitacost
$ 18.19
Pure Formulas
$ 18.19
Amazon
$ 14.98
Walmart
$ 18.19
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Analysis

The serving supplies 425 mg of elemental magnesium from magnesium malate trihydrate plus a clearly listed malic acid contribution. The label distinguishes elemental magnesium from the much larger compound weight, which improves dose clarity.

Malate is a useful organic form for systemic magnesium support. Three tablets and 3 g of carbohydrate per serving add bulk, while the dose sits near the high end of supplemental use.

It fits users seeking malate at an economical cost and who tolerate a large serving. Smaller or divided intake may be more comfortable for routine daily use.

Who is it for
  • Adults specifically seeking magnesium malate
  • People comfortable with three tablets
  • Users wanting a substantial magnesium serving
Best for
  • Systemic magnesium support
  • Malate-focused supplementation
  • Value-conscious high-dose use

Pros

  • Uses magnesium malate trihydrate
  • Clearly states 425 mg elemental magnesium
  • Discloses malic acid separately
  • Good value for an organic form

Cons

  • Large amount may cause digestive upset
  • Requires three tablets
  • Adds 3 g of carbohydrate
  • No patented material is identified

Warnings

  • The 425 mg serving of supplemental magnesium may cause loose stools, cramping, or nausea; a smaller divided amount may be easier to tolerate.
  • Magnesium can reduce absorption of tetracycline or quinolone antibiotics; follow the prescriber or pharmacist’s spacing instructions.
  • Magnesium can interfere with levothyroxine absorption and should be separated according to medication guidance.
  • People with significantly reduced kidney function can accumulate magnesium and need clinician-guided use.

Nutrient quality

82 Highest impact

Magnesium malate is a well-absorbed organic form with a useful malic-acid carrier. The elemental amount is substantial and near the upper end of routine supplementation, while the larger amount may cause loose stools or discomfort in sensitive users.

Ingredient transparency

74 High impact

Elemental magnesium and compound weight are shown, though repeated source entries make the total presentation confusing. Serving totals are apparent, but full directions and inactive ingredients are not supplied.

Customer satisfaction

72 High impact

The supplied average rating is strong. The exceptionally large rating base makes the average highly stable, while complaint and firsthand experience details are unavailable.

Value for money

86 Highest impact

Formula quality supports the asking position well. The serving value is highly competitive within the category.

Report analysis

Goals

General Health
General Health
Impact
Highest effect
B+ Goal FitA- Strength of SupportC CoverageA Formula Quality
Magnesium · 3.75 Gram(s)

Magnesium malate provides focused support for normal muscle, nerve, and energy-related functions. Clear separation of elemental magnesium from compound weight improves label transparency.

The narrow formula does not cover broader vitamin or fatty-acid needs. A 425 mg magnesium serving may cause loose stools or abdominal discomfort in sensitive users.

Study evidence
Magnesium Supportive 114 studies
Stress Relief
Stress Relief
Impact
Highest effect
C+ Goal FitA Strength of SupportC+ CoverageA+ Formula Quality
Magnesium · 3.75 Gram(s)

Magnesium malate supplies 425 mg of magnesium for foundational nervous-system and muscle support. Stress relief is most likely when low magnesium status contributes to tension, so the effect is supportive rather than directly adaptogenic.

Magnesium malate is a reasonably bioavailable form with a clearly stated elemental amount. 425 mg of supplemental magnesium may cause loose stools or abdominal discomfort in sensitive users.

Study evidence
Magnesium Supportive 13 studies
Heart Health
Heart Health
Impact
High effect
B Goal FitB+ Strength of SupportC CoverageA+ Formula Quality
Magnesium · 3.75 Gram(s)

Magnesium supports normal heart rhythm and vascular tone when intake is inadequate. The 425 mg amount is clearly stated as magnesium malate.

The high supplemental amount may cause diarrhea or abdominal discomfort in sensitive users. The focused formula does not address lipid or cardiac-energy pathways.

Study evidence
Magnesium Supportive 158 studies
Energy
Energy
Impact
High effect
C+ Goal FitA Strength of SupportD+ CoverageA Formula Quality
Magnesium · 3.75 Gram(s)

Magnesium malate provides a well-absorbed mineral cofactor for ATP production and is more suitable than magnesium oxide for correcting low intake. Malate also participates in energy metabolism, though evidence for a distinct energy benefit remains limited.

The label clearly separates elemental magnesium from the larger compound amount and provides a substantial serving. The high supplemental magnesium amount may cause loose stools or cramping, so tolerance can limit practical use.

Study evidence
Magnesium Supportive 4 studies
Cardiovascular Support
Cardiovascular Support
Impact
High effect
B Goal FitA- Strength of SupportD+ CoverageB+ Formula Quality
Magnesium · 3.75 Gram(s)

Magnesium supports vascular relaxation and normal electrical rhythm, giving this focused supplement a clear cardiovascular role. Magnesium malate is a well-absorbed organic form, although the label repeats compound and malic-acid amounts.

The single-mineral approach does not address lipids, endothelial nitric oxide, or antioxidant protection. The 425 mg amount may cause loose stools in sensitive users.

Study evidence
Magnesium Supportive 123 studies
Bone Health
Bone Health
Impact
High effect
B- Goal FitA- Strength of SupportD CoverageB+ Formula Quality
Magnesium · 3.75 Gram(s)

Magnesium malate provides a well-absorbed mineral form at a substantial amount. It can support bone-related enzyme activity and mineral balance but cannot replace a broader calcium, vitamin D, and vitamin K strategy.

Elemental and compound amounts are clearly distinguished, which improves label transparency. The high magnesium serving may cause loose stools or stomach upset in sensitive users.

Study evidence
Magnesium Supportive 48 studies

Ingredients

IngredientAmount per serving
Calories
10 Calorie(s)
Total Carbohydrates
3 Gram(s)
Magnesium (Magnesium Malate Trihydrate)
 425 mg
Sodium
5 mg
Magnesium Malate Trihydrate
3.75 Gram(s)
Malic Acid (Magnesium Malate Trihydrate)
 2.5 Gram(s)
Adults 18–50
Report overview
Magnesium (Magnesium Malate Trihydrate) · 425 mg OverallScore83
B- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyA+ Value

Magnesium malate is a well-absorbed organic form, and the label distinguishes 425 mg elemental magnesium from the larger compound weight. The dose is close to the standard upper target, while no patented or fully reacted chelation claim is given. Its below-median cost makes the premium form economical, though the dose may be more than some users tolerate comfortably.

View ingredientView products
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88 Performance

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<p>Magnesium bisglycinate supplies a well-absorbed form at a practical, moderate amount. Compared with the original, its magnesium form, dose clarity, and focused design offer a stronger quality-oriented option.</p>
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Magnesium Bisglycinate 200 mg

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Krebs Magnesium Potassium Complex

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<p>Magnesium lysinate and malate provide favorable forms at a useful amount, with a modest potassium contribution. Its lower supplied serving cost makes it a more economical magnesium option than the original.</p>
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<p>A well-aligned amount of magnesium citrate delivers useful absorption in a focused powder. Its lower supplied serving cost makes it a more economical magnesium option than the original.</p>
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Magnesium Glycinate

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<p>Magnesium glycinate is a well-absorbed form that is often gentle on digestion. Its stated magnesium form, practical dose, and lower serving cost offer a stronger balance of quality and value than the original.</p>
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<p>A substantial amount of magnesium citrate offers useful absorption and a focused formula. Its stated magnesium form, practical dose, and lower serving cost offer a stronger balance of quality and value than the original.</p>
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<p>A substantial amount of magnesium citrate combines useful absorption with a focused single-active design. Its stated magnesium form, practical dose, and lower serving cost offer a stronger balance of quality and value than the original.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The effect of food, vitamin, or mineral supplements on chronic constipation in adults: A systematic review and meta-analysis of randomized controlled trials.
    van der Schoot A; Creedon A; Whelan K; Dimidi E · Neurogastroenterology and motility · 2023
    Meta-analysis787 participants8 studies pooledDigestive Health forMagnesium
  2. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  3. Diagnosis of magnesium-induced diarrhea.
    Fine KD; Santa Ana CA; Fordtran JS · The New England journal of medicine · 1991
    Clinical trial19 participantsDigestive Health forMagnesium
  4. Lactobacillus casei rhamnosus Lcr35 in children with chronic constipation.
    Bu LN; Chang MH; Ni YH; Chen HL; Cheng CC · Pediatrics international : official journal of the Japan Pediatric Society · 2007
    Randomized trial45 participantsDigestive Health forMagnesium
  5. Lactobacillus reuteri DSM 17938 and Magnesium Oxide in Children with Functional Chronic Constipation: A Double-Blind and Randomized Clinical Trial.
    Kubota M; Ito K; Tomimoto K; Kanazaki M; Tsukiyama K; Kubota A; Kuroki H; Fujita M; Vandenplas Y · Nutrients · 2020
    Randomized trial60 participantsDigestive Health forMagnesium
  6. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  7. Magnesium-Rich Mineral Water Improves Stool Consistency and Bowel Habits in Healthy Subjects: A Randomized Controlled Trial.
    Yoneda H; Tomita T; Kitano T; Morishita D; Kodani M; Nishii N; Sei H; Eda H; Sato T; Kawai M; Yokoyama Y; Igeta M; Okugawa T; Fukui H; Shinzaki S · Neurogastroenterology and motility · 2026
    Randomized trial40 participantsDigestive Health forMagnesium
  8. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  9. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  10. Effect of the laxative magnesium oxide on gastrointestinal functional recovery in fast-track colonic resection: a double-blind, placebo-controlled randomized study.
    Andersen J; Christensen H; Pachler JH; Hallin M; Thaysen HV; Kehlet H · Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2012
    Randomized trial49 participantsDigestive Health forMagnesium
  11. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  12. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  13. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  14. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  15. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  16. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  17. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  18. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  19. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  20. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  21. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  22. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  23. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  24. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  25. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  26. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  27. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  28. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  29. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  30. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  31. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  32. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  33. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  34. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  35. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  36. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  37. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  38. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  39. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  40. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  41. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  42. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  43. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium