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B-Complex 75

Solaray
4.7
★ ★ ★ ★ ★
(2902 ratings)
PABA 75 mg
Thiamin 75 mg
Vitamin B6 75 mg
Riboflavin 75 mg
Niacin 75 mg
Vitamin B5 75 mg
Folate 400 mcg
Product Image
Score73
Broad and transparent, but conventional forms and aggressive B6 dosing make it better for a defined need than casual daily use.
How scoring works
Quantity:100 VegCap(s) • (100 servings)
Goals:
Energy
General Health
Metabolism Boost

Score 73

Broad and transparent, but conventional forms and aggressive B6 dosing make it better for a defined need than casual daily use.
How scoring works

Also available as

4 options
50 mg • 250 VegCap(s) servings 50 mg • 250 VegCap(s) • 250 servings $33.39 ($0.13 per serving) 50 mg • 100 VegCap(s) servings 50 mg • 100 VegCap(s) • 100 servings $16.09 ($0.16 per serving) 100 mg • 250 VegCap(s) servings 100 mg • 250 VegCap(s) • 250 servings $51.99 ($0.20 per serving) 100 mg • 100 VegCap(s) servings 100 mg • 100 VegCap(s) • 100 servings $23.20 ($0.23 per serving)
$22.69($0.22 per serving)
Walmart
$ 22.69
Amazon
$ 22.69
Vitacost
$ 22.69
iHerb
$ 22.69
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Analysis

The formula supplies the complete B-vitamin group at substantial amounts and adds choline, inositol, and PABA. It is most relevant for correcting dietary gaps rather than creating immediate energy in someone whose status is already adequate.

Folic acid, cyanocobalamin, pyridoxine hydrochloride, and standard riboflavin are conventional choices. Choline bitartrate is not brain-targeted, and the matching doses of several extras look tidy on the label without creating equal functional value.

A one-capsule serving and clear amounts make use straightforward. The high vitamin B6 amount is the main drawback for prolonged daily use, particularly when other fortified foods or supplements are involved.

Who is it for
  • Adults seeking a high-potency B-complex
  • Users who prefer a one-capsule serving
  • People addressing a known B-vitamin gap
Best for
  • Broad B-vitamin supplementation
  • Normal energy metabolism
  • Short-term high-potency use

Pros

  • Provides the full B-vitamin group
  • Clearly discloses all amounts
  • Convenient one-capsule serving
  • Includes choline and inositol

Cons

  • Uses basic folic acid and cyanocobalamin
  • Uses standard pyridoxine rather than active B6
  • Choline is modest and not brain-targeted
  • PABA and inositol add limited practical depth

Warnings

  • The 75 mg vitamin B6 amount may cause tingling, numbness, or peripheral nerve problems with prolonged use, especially when combined with other B6 sources.

Nutrient quality

64 Moderate impact

The full B-vitamin profile is useful, but folic acid, cyanocobalamin, and pyridoxine are basic forms. Several nutrients are heavily dosed, with vitamin B6 posing the main balance concern.

Ingredient transparency

76 High impact

Most amounts are clear, though the thiamine total is repeated across two naming entries. Daily directions and inactive ingredients are not supplied.

Customer satisfaction

71 High impact

The aggregate rating is very strong and backed by substantial volume. No detailed experience reports are supplied, so recurring complaints and purpose fit remain uncertain.

Value for money

80 High impact

A large supply and full B-complex profile provide strong cost value. Excessive vitamin B6 and basic forms reduce the usefulness of that value for daily use.

Report analysis

Goals

Energy
Energy
Impact
High effect
B+ Goal FitC+ Strength of SupportC- CoverageB+ Formula Quality
Vitamin B5 · 75 mgRiboflavin · 75 mgThiamin · 75 mgVitamin B12 · 75 mcg

The focused B-complex directly supports carbohydrate, fat, and amino-acid metabolism but does not provide acute or mitochondrial energy actives. B vitamins have established metabolic roles, although supplementation mainly helps energy when intake or status is inadequate.

Most B vitamins are high potency, but vitamin B12 is below the preferred threshold and vitamin B6 is unusually high for long-term use. Amounts are fully disclosed, but cyanocobalamin, pyridoxine hydrochloride, folic acid, and standard riboflavin are basic forms.

Study evidence
Riboflavin Mixed 6 studies
General Health
General Health
Impact
High effect
B- Goal FitB- Strength of SupportC CoverageB Formula Quality
Folate · 400 mcgVitamin B12 · 75 mcg

A high-dose B-complex supports energy metabolism, nervous-system function, and blood-cell formation. Its focus is narrower than a comprehensive general-health formula because it supplies no vitamin D, essential minerals, or fatty acids.

Every listed ingredient has an amount, but folic acid and cyanocobalamin are basic forms and several nonessential additions are present at matching doses. The high pyridoxine amount raises a meaningful neuropathy concern with long-term daily use, especially when combined with other vitamin B6 sources.

Study evidence
Folate Supportive 80 studies
Metabolism Boost
Metabolism Boost
Impact
Moderate effect
D+ Goal FitC+ Strength of SupportD+ CoverageA- Formula Quality
Biotin · 75 mcgNiacin · 75 mgVitamin B12 · 75 mcgRiboflavin · 75 mgThiamin · 75 mgVitamin B5 · 75 mgVitamin B6 · 75 mg

High-potency B vitamins support the conversion of food into cellular energy. They do not directly stimulate thermogenesis, thyroid output, or fat oxidation.

The fully disclosed one-capsule formula provides substantial amounts across the B-vitamin group. Its high vitamin B6 amount raises nerve-injury risk with prolonged use or stacking with other B6 supplements.

Study evidence
Riboflavin Mixed 5 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies

Ingredients

IngredientAmount per serving
Thiamine (Thiamine Mononitrate, Vitamin B1)
 75 mg
Riboflavin (Vitamin B2)
 75 mg
Niacin (Niacinamide)
 75 mg
Vitamin B6 (Pyridoxine Hydrochloride)
 75 mg
Folic Acid
400 mcg
Vitamin B12 (Cyanocobalamin)
 75 mcg
Biotin
75 mcg
Pantothenic Acid (Calcium Pantothenate)
 75 mg
Choline Bitartrate
75 mg
PABA
75 mg
Inositol
75 mg
Adults 18–50
Report overview
Thiamin (Thiamine Mononitrate, Vitamin B1) · 75 mg OverallScore88
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

A high-potency dose supports targeted thiamine use, although mononitrate remains a standard form. The exact amount is clearly labeled in a simple capsule format. Low serving cost and a substantial supply create strong value.

View ingredientView products
PABA · 75 mg OverallScore88
A Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB- Value

The clearly listed 75 mg PABA amount fits a standard B-complex or high-potency combination dose. No purity grade is stated, but immediate release is appropriate and the exact amount is easy to verify. Cost efficiency is moderate, although the active amount does not reach the leading value tier.

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Vitamin B6 (Pyridoxine Hydrochloride) · 75 mg OverallScore79
C+ Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyA+ Value

Pyridoxine hydrochloride is a less direct B6 form, though the included riboflavin can support its conversion to the active coenzyme. The 75 mg total is a higher dose, and long-term stacking with other B6 products could increase tingling or numbness from nerve injury. The one-capsule serving is practical and offers favorable value for its B-complex category.

View ingredientView products
Loading alternative details
81 Performance

Coenzyme B-Complex Caps

Country Life
<p>Multiple coenzyme forms improve the quality of riboflavin, folate, vitamin B12, and other B nutrients compared with a mostly conventional formula. Vitamin B6 remains elevated, and choline is only modestly dosed.</p>
79 Performance

CoEnzyme B-Complex

KAL
<p>Active and conventional B-vitamin forms provide broad coverage with a more restrained vitamin B6 amount than many B-50 or B-75 formulas. The chewable format adds carbohydrates, and the mixed vitamin B12 strategy is less efficient than a fully active approach.</p>
73 Performance

Glycogenics

Metagenics
<p>Methylfolate and methylcobalamin strengthen form quality within a broad vitamin formula. High niacin and pyridoxine remain less balanced for routine use, and the premium serving cost is difficult to justify.</p>
77 Budget

B-50

NOW
<p>A large supply provides the full standard B-vitamin pattern at lower serving cost. Basic forms and a high vitamin B6 amount remain important limitations for sustained daily use.</p>
77 Budget

B-50 Complex 50 mg

Source Naturals
<p>Broad B-vitamin coverage comes at very favorable serving value while preserving the original energy-metabolism focus. High folate and vitamin B6 amounts still reduce dose balance for routine daily use.</p>
76 Budget

Hi Potency B Complex

Natural Factors
<p>A complete high-potency B-complex offers broad nutritional coverage at a low or comparable serving cost. High folate and vitamin B6 remain unnecessarily aggressive for unsupervised long-term use.</p>
79 Value

Basic-B Caps

Country Life
<p>A complete, fully disclosed B-complex delivers useful metabolic coverage at strong serving value. Most forms are conventional and vitamin B6 is still higher than necessary, but there is no hidden active blend.</p>
77 Value

B-50

NOW
<p>Broad B-vitamin amounts and a large supply provide strong value for focused energy-metabolism support. Basic forms and high vitamin B6 make the formula better suited to limited or need-based use than indefinite daily use.</p>
75 Value

B-Complex 50

Bluebonnet
<p>A complete B-vitamin pattern provides focused nutritional coverage at a reasonable serving cost. Basic forms and high vitamin B6 limit long-term appeal, but the formula remains a practical value alternative.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physiological and performance responses to supplementation with thiamin and pantothenic acid derivatives.
    Webster MJ · European journal of applied physiology and occupational physiology · 1998
    Randomized trial6 participantsMetabolism Boost forVitamin B5
  2. Riboflavin and riboflavin-derived cofactors in adolescent girls with anorexia nervosa.
    Capo-chichi CD; Guéant JL; Lefebvre E; Bennani N; Lorentz E; Vidailhet C; Vidailhet M · The American journal of clinical nutrition · 1999
    Clinical trial34 participantsMetabolism Boost forRiboflavin
  3. Disorders of flavin adenine dinucleotide metabolism: MADD and related deficiencies.
    Mereis M; Wanders RJA; Schoonen M; Dercksen M; Smuts I; van der Westhuizen FH · The international journal of biochemistry & cell biology · 2024
    Systematic reviewMetabolism Boost forRiboflavin
  4. Apolipoprotein E and sex modulate fatty acid metabolism in a prospective observational study of cognitive decline.
    González-Domínguez R; Castellano-Escuder P; Lefèvre-Arbogast S; Low DY; Du Preez A; Ruigrok SR; Lee H; Helmer C; Pallàs M; Urpi-Sarda M; Sánchez-Pla A; Korosi A; Lucassen PJ; Aigner L; Manach C; Thuret S; Samieri C; Andres-Lacueva C · Alzheimer's research & therapy · 2022
    Observational studyMetabolism Boost forVitamin B5
  5. Exploring auxotrophy and engineering vitamin B6 prototrophy in the acetogen Clostridium sp. AWRP.
    Kwon SJ; Lee J; Lee HS · Applied and environmental microbiology · 2024
    Clinical trialMetabolism Boost forVitamin B5
  6. Anaemia during pregnancy: could riboflavin deficiency be implicated?
    Duffy B; McNulty H; Ward M; Pentieva K · The Proceedings of the Nutrition Society · 2026
    Narrative reviewMetabolism Boost forRiboflavin
  7. Pantothenate utilization by Plasmodium as a target for antimalarial chemotherapy.
    Spry C; van Schalkwyk DA; Strauss E; Saliba KJ · Infectious disorders drug targets · 2010
    Narrative reviewMetabolism Boost forVitamin B5
  8. Pantothenate synthetase is essential but not limiting for pantothenate biosynthesis in Arabidopsis.
    Jonczyk R; Ronconi S; Rychlik M; Genschel U · Plant molecular biology · 2008
    OtherMetabolism Boost forVitamin B5
  9. Optimum nutrition: thiamin, biotin and pantothenate.
    Bender DA · The Proceedings of the Nutrition Society · 1999
    Narrative reviewMetabolism Boost forVitamin B5
  10. Serum metabolites of hypertension among Chinese adolescents aged 12-17 years.
    Sun J; Ding W; Liu X; Zhao M; Xi B · Journal of human hypertension · 2022
    Other77 participantsMetabolism Boost forVitamin B5
  11. Metabolic profiles of exercise in patients with McArdle disease or mitochondrial myopathy.
    Delaney NF; Sharma R; Tadvalkar L; Clish CB; Haller RG; Mootha VK · Proceedings of the National Academy of Sciences of the United States of America · 2018
    OtherMetabolism Boost forVitamin B5
  12. Dual-omics analysis reveals B vitamin regulation and metabolism in Areca Catechu inflorescence.
    Jiang W; Liu X; Li W; Yang J; Li P; Xie M; Zhou G · BMC genomics · 2026
    OtherMetabolism Boost forVitamin B5
  13. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  14. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  15. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  16. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  17. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Boost forRiboflavin
  18. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsGeneral Health forFolate
  19. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsGeneral Health forFolate
  20. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsGeneral Health forFolate
  21. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewGeneral Health forFolate
  22. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledGeneral Health forFolate
  23. Effects of riboflavin and folic acid supplementation on plasma homocysteine levels in healthy subjects.
    Chuang CZ; Boyles A; Legardeur B; Su J; Japa S; Lopez-S A · The American journal of the medical sciences · 2006
    Non-randomized trial34 participantsMetabolism Boost forRiboflavin
  24. Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children and Adults.
    Dhir S; Tarasenko M; Napoli E; Giulivi C · Frontiers in psychiatry · 2026
    Narrative reviewMetabolism Boost forThiamin
  25. Plasma vitamin profiles and their associations with metabolic health and mental wellbeing in midlife Asian women.
    Tan KML; Tint MT; Cabral RM; Lau R; Kee MZL; Garg V; De Iorio M; Tan SSL; Eriksson JG · Scientific reports · 2026
    Cohort study662 participantsMetabolism Boost forThiamin
  26. High-resolution plasma metabolomics and thiamine status in critically Ill adult patients.
    Gundogan K; Nellis MM; Ozer NT; Ergul SS; Sahin GG; Temel S; Yuksel RC; Teeny S; Alvarez JA; Sungur M; Jones DP; Ziegler TR · Metabolomics : Official journal of the Metabolomic Society · 2024
    Cross-sectional study76 participantsMetabolism Boost forThiamin
  27. Pathophysiology, prevention, and treatment of beriberi after gastric surgery.
    Wilson RB · Nutrition reviews · 2021
    Narrative reviewMetabolism Boost forThiamin
  28. Red blood cell transketolase activity and the effect of thiamine supplementation in patients with chronic liver disease.
    Rossouw JE; Labadarios D; Krasner N; Davis M; Williams R · Scandinavian journal of gastroenterology · 1978
    Single-arm trialMetabolism Boost forThiamin
  29. Plasma vitamin B6 vitamers before and after oral vitamin B6 treatment: a randomized placebo-controlled study.
    Bor MV; Refsum H; Bisp MR; Bleie Ø; Schneede J; Nordrehaug JE; Ueland PM; Nygard OK; Nexø E · Clinical chemistry · 2003
    Randomized trial90 participantsMetabolism Boost forVitamin B6
  30. Dietary one-carbon metabolism nutrients and risk of MASLD progression: a prospective cohort study.
    Shen L; Wang K; Li R; Li Y; Guo Y; Li F; Yuan J; Yang Z; Xia B; Lin X · European journal of clinical nutrition · 2026
    Cohort study46,800 participantsMetabolism Boost forVitamin B6
  31. Associations of Vitamin B6 Intake and Plasma Pyridoxal 5'-Phosphate with Plasma Polyunsaturated Fatty Acids in US Older Adults: Findings from NHANES 2003-2004.
    Kim H; Enrione EB; Narayanan V; Li T; Campa A · Nutrients · 2022
    Cross-sectional study461 participantsMetabolism Boost forVitamin B6
  32. Influence of oral contraceptives, pyridoxine (vitamin B6), and tryptophan on carbohydrate metabolism.
    Adams PW; Wynn V; Folkard J; Seed M · Lancet (London, England) · 1976
    Clinical trial46 participantsMetabolism Boost forVitamin B6
  33. Effect of oral contraceptives and vitamin B6 deficiency on carbohydrate metabolism.
    Rose DP; Leklem JE; Brown RR; Linkswiler HM · The American journal of clinical nutrition · 1975
    Clinical trialMetabolism Boost forVitamin B6