BioActive Complete B-Complex
Life Extension
BioActive Complete B-Complex
4.8
★ ★ ★ ★ ★
(94580 ratings)
Vitamin B6 100 mg
Thiamin 100 mg
PABA 50 mg
Vitamin B12 300 mcg
Riboflavin 75 mg
Vitamin B5 500 mg
Biotin 1000 mcg
Score 95.0
A premium, high-potency B-complex from Life Extension featuring active forms of B vitamins for superior bioavailability and comprehensive support for energy, brain health, and metabolism.
Quantity: 60 Capsule(s)Servings size: 2 Vegetarian Capsule(s) (30 servings)
Selected goals:
Other goals:
Energy
Brain Health
Mood Support
General Health
Cognitive Support
leaderboard Score 95.0
A premium, high-potency B-complex from Life Extension featuring active forms of B vitamins for superior bioavailability and comprehensive support for energy, brain health, and metabolism.
insights Analysis
Life Extension's BioActive Complete B-Complex is a high-potency supplement meticulously formulated to provide superior B vitamin support. It stands out by incorporating active forms of B2, B6, B9 (folate), and B12, which are crucial for individuals who may have genetic variations that impair the conversion of inactive vitamin forms into their usable counterparts. Beyond the core B vitamins, the inclusion of Inositol and PABA adds to its comprehensive profile, supporting various bodily functions including nerve health and skin integrity. Reviews consistently praise its effectiveness in boosting energy and improving mood, though some users note the premium price reflects the advanced formulation and high dosages.
- Contains active/coenzymated forms of key B vitamins (Methylcobalamin B12, L-5-Methyltetrahydrofolate Folate, Pyridoxal 5-Phosphate B6, Riboflavin 5-Phosphate B2), enhancing absorption and utilization.
- Offers a comprehensive spectrum of all eight essential B vitamins, plus Inositol and PABA, ensuring broad support for various bodily functions.
- Features high dosages of each B vitamin, making it effective for individuals with deficiencies or increased nutritional needs.
- Produced by Life Extension, a highly reputable brand known for its rigorous quality control and science-backed formulations.
- Boasts an extremely high volume of positive online reviews, indicating widespread customer satisfaction and perceived effectiveness.
- The price per serving is relatively high compared to many other B-complex supplements on the market, which may not be suitable for all budgets.
- For individuals without specific B vitamin deficiencies, the high dosages might be excessive, potentially leading to unnecessary expenditure on water-soluble vitamins that are simply excreted.
- The listing for Calcium and Pantothenic Acid could be clearer, as calcium is listed as 'Dicalcium Phosphate' and 'Calcium D-Pantothenate' with varying quantities, which may cause slight confusion.
- While generally safe, high doses of certain B vitamins, particularly Vitamin B6 (pyridoxine), can potentially lead to peripheral neuropathy in sensitive individuals over long periods.
- Although the niacin in this product is primarily Niacinamide, which is non-flushing, very sensitive individuals might still experience mild skin flushing.
- Individuals who are pregnant, nursing, taking medications, or have pre-existing medical conditions should consult a healthcare professional before taking this or any high-potency supplement.
$9.00($0.30 per serving)
 Pure Formulas | $ 9.00 | |
 Vitacost | $ 9.00 | |
 iHerb | $ 9.00 |
bolt Effectiveness for goals
These are active or coenzyme forms of B vitamins, meaning the body can utilize them directly without needing to convert them first. This direct usability may offer benefits for individuals with genetic variations affecting B vitamin metabolism. For example, methylcobalamin is a biologically active form of vitamin B12, and L-5-methyltetrahydrofolate is the primary biologically active form of folate.
B vitamins are interdependent and work synergistically in many bodily processes, especially energy production and cell metabolism. A complete B-complex ensures that all necessary cofactors are present for these functions. This comprehensive approach supports overall well-being and various metabolic pathways.
B vitamins play crucial roles as coenzymes in converting food into usable energy. Thiamine, riboflavin, niacin, pantothenic acid, and biotin are particularly important in various metabolic pathways that break down carbohydrates, fats, and proteins. This process is fundamental for cellular energy production.
Inositol is a pseudovitamin often associated with the B-vitamin family, involved in cellular signaling and nerve function. PABA (Para-aminobenzoic acid) is also sometimes considered part of the B-complex and plays a role in folate metabolism. Both are included for their supportive roles alongside the core B vitamins.
Niacin (Vitamin B3) can cause a temporary flushing sensation in some individuals. Niacinamide is a non-flushing form of Niacin, which provides the benefits of B3 without this common side effect. Including both forms helps ensure comprehensive niacin activity while minimizing discomfort.
schedule Dosage, timing & forms
Many experts suggest taking B vitamins in the morning, potentially with breakfast. This is because B vitamins can sometimes provide an energy boost, which may interfere with sleep if taken later in the day. Taking them with food can also help minimize potential stomach upset.
Active forms like L-5-Methyltetrahydrofolate (active folate) and Methylcobalamin (active B12) are readily usable by the body without requiring metabolic conversion. This can be particularly beneficial for individuals with genetic variations that affect nutrient metabolism. They ensure more direct bioavailability for various metabolic functions.
Generally, calcium does not significantly impair the absorption of most B vitamins when taken as part of a supplement. Some forms of calcium, like dicalcium phosphate, are often used as a filler or a source of calcium, and are not typically known to create strong negative interactions with B vitamins. It's usually safe to take them together.
While B vitamins can be taken on an empty stomach, consuming them with food may reduce the likelihood of stomach discomfort or nausea. Food can also assist in the absorption of certain fat-soluble vitamins, though most B vitamins are water-soluble. Always follow specific product instructions if provided.
Niacin (nicotinic acid) is known for its ability to affect cholesterol levels and can cause a 'niacin flush' in higher doses. Niacinamide (nicotinamide) generally does not cause the flush and is more commonly used for its cellular energy and DNA repair roles. Both forms contribute to overall Niacin requirements and various metabolic processes, providing a broader spectrum of benefits.
health_and_safety Safety & interactions
Yes, riboflavin, or vitamin B2, is known to cause a harmless bright yellow or greenish-yellow discoloration of the urine. This is a common and expected effect as the body excretes excess riboflavin, which is a water-soluble vitamin.
Some individuals may experience a temporary 'niacin flush,' characterized by redness, warmth, itching, or tingling, particularly with higher doses of nicotinic acid (niacin). The niacinamide form present in this supplement is generally less likely to cause this effect.
Yes, high doses of biotin, such as those typically found in B-complex supplements, can interfere with certain laboratory tests, including those for thyroid function and cardiac biomarkers. It's important to inform your healthcare provider about any biotin supplementation before undergoing blood tests.
Very high doses of vitamin B6 (pyridoxine) over extended periods have been linked to peripheral neuropathy, characterized by nerve damage leading to numbness or tingling. The forms of B6 in this product are generally well-tolerated at the indicated dosages.
While B vitamins are water-soluble and excess amounts are generally excreted, it does not mean they are safe in all amounts. Very high intakes of certain B vitamins, such as B6 and niacin, can lead to specific side effects or toxicity. Adhering to recommended dosages is important.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Thiamine | 100 mg |
Riboflavin | 75 mg |
Niacin | 100 mg NE |
Vitamin B6 | 100 mg |
Folate | 680 mcg DFE |
Vitamin B12 | 300 mcg |
Biotin | 1000 mcg |
Pantothenic Acid | 500 mg |
Calcium | 90 mg |
Inositol | 100 mg |
PABA | 50 mg |
Categories
Vitamin B12 95.0
The product contains 300mcg of Methylcobalamin, which is the active and most bioavailable form of Vitamin B12. This is superior to the more common cyanocobalamin, as it does not require metabolic conversion and is readily utilized by the body, making it highly effective.
Vitamin B6 95.0
This B-complex includes both Pyridoxal 5-Phosphate (P5P) and Pyridoxine Hydrochloride, with P5P being the active coenzyme form that the body can directly utilize. The high total dosage of 100mg ensures comprehensive support for neurotransmitter synthesis and protein metabolism.
Riboflavin 95.0
Featuring both Riboflavin and its active form, Riboflavin 5-Phosphate, at a total of 75mg, this product ensures optimal utilization. Riboflavin is essential for cellular energy production and acts as an antioxidant, and the active form maximizes its benefits.
Goals
Energy 95.0
B vitamins are fundamental coenzymes in the body's energy production pathways. The comprehensive profile and active forms of B vitamins in this complex ensure efficient metabolic conversion of food into energy, directly supporting sustained energy levels.
Brain Health 95.0
This B-complex is excellent for brain health due to its inclusion of active forms of B6, B9 (folate), and B12. These vitamins are crucial for neurotransmitter synthesis, nerve signal transmission, and maintaining optimal cognitive function, directly benefiting brain health.
Cognitive Support 95.0
Similar to brain health, the active B vitamins (especially B6, Folate, and B12) are indispensable for cognitive functions such as memory, focus, and mental clarity. Their direct involvement in neurological processes makes this complex highly effective for cognitive support.
Recommended Alternatives
90 Value 
B-Complex
Paradise Earth's Blend
4.7
★★★★★
(4459 ratings)
This product offers excellent value by including several active B-vitamin forms (Methylcobalamin, L-Methylfolate, P5P, Riboflavin 5-Phosphate, Benfotiamine) comparable to the original, but at a more competitive price of $20 per serving. Additionally, it integrates superfood and adaptogen blends, providing an enhanced nutritional profile beyond basic B-complex, making it a well-rounded and high-quality choice for the price.
88 Value 
Activated B-Complex High Bioavailability
Swanson
4.9
★★★★★
(1190 ratings)
Swanson's Activated B-Complex provides a compelling value proposition by explicitly focusing on bioavailable forms like Benfotiamine, Methylcobalamin, Pyridoxal 5-Phosphate, and Calcium L-5-Methyltetrahydrofolate at $20 per serving. This makes it an excellent choice for consumers seeking the benefits of active B vitamins without the higher price tag of the Life Extension original, ensuring efficient nutrient absorption.
85 Value 
Hi Potency B Complex
Natural Factors
4.7
★★★★★
(13054 ratings)
At $12 per serving, Natural Factors Hi Potency B Complex offers a strong value by providing a comprehensive 'B50' dose from a reputable brand. While it may not feature all the active forms found in the Life Extension product, it delivers a solid and effective B-complex for daily needs at a significantly more accessible price, balancing quality and affordability.
98 Performance 
Two-Per-Day Capsules
Life Extension
4.7
★★★★★
(85932 ratings)
This is a superior alternative because it is a comprehensive multivitamin from the same reputable brand, Life Extension, offering an even broader spectrum of nutrients beyond just B vitamins. It maintains the high quality and active forms of B vitamins found in the original product while adding essential minerals, antioxidants, and other beneficial compounds for more holistic health support.
97 Performance 
Advanced Nutrients
Thorne
4.6
★★★★★
(851 ratings)
Thorne is a highly respected brand known for its exceptional purity and use of highly bioavailable nutrient forms. This multivitamin provides active B vitamins (e.g., Methylcobalamin, Pyridoxal 5-Phosphate, Riboflavin 5'-Phosphate Sodium, Folate as Methylfolate) at clinically relevant dosages, combined with a robust array of other high-quality vitamins and minerals, making it a step up for those seeking premium, comprehensive nutritional support.
100 Performance 
Life Extension Mix Capsules
Life Extension
4.7
★★★★★
(492 ratings)
Representing the pinnacle of multi-nutrient supplementation, Life Extension Mix is the brand's most advanced formula, offering exceptionally high potencies and the most bioavailable forms of all vitamins, including an even more robust B-complex profile than the original. It includes a vast array of specialized nutrients, botanicals, and antioxidants, providing unmatched comprehensive support for overall health and longevity.
75 Budget 
B 100 Complex
Spring Valley
4.7
★★★★★
(401 ratings)
This Spring Valley B 100 Complex offers a comprehensive blend of B vitamins at a potency of 100mg per vitamin, similar to the analyzed product in general dosage, but at a significantly lower price point of $9 per serving, making it a budget-friendly option for broad B-vitamin support. However, it uses non-active forms of vitamins like B12 (Cyanocobalamin) and Folate, which are less bioavailable than the forms in the Life Extension product.
70 Budget 
B-Complex plus Vitamin C
21st Century
4.7
★★★★★
(24336 ratings)
At only $6 per serving, this 21st Century B-Complex is one of the most affordable options available, also including Vitamin C for added immune and antioxidant support. While its B vitamin dosages are generally lower (e.g., B1 15mg, B12 12mcg) and it uses non-active forms, it provides basic B vitamin coverage at a very accessible price.
72 Budget 
B 50 Complex
Thompson
4.7
★★★★★
(2864 ratings)
The Thompson B 50 Complex is a cost-effective alternative at $8 per serving, offering a good foundational dose of 50mg for most B vitamins. While not as high potency as the original and using standard non-active forms, it serves as a solid option for daily maintenance of B vitamin levels for those on a tighter budget.
90 Value
B-Complex
Paradise Earth's Blend
4.7
★★★★★
(4459 ratings)
This product offers excellent value by including several active B-vitamin forms (Methylcobalamin, L-Methylfolate, P5P, Riboflavin 5-Phosphate, Benfotiamine) comparable to the original, but at a more competitive price of $20 per serving. Additionally, it integrates superfood and adaptogen blends, providing an enhanced nutritional profile beyond basic B-complex, making it a well-rounded and high-quality choice for the price.
88 Value
Activated B-Complex High Bioavailability
Swanson
4.9
★★★★★
(1190 ratings)
Swanson's Activated B-Complex provides a compelling value proposition by explicitly focusing on bioavailable forms like Benfotiamine, Methylcobalamin, Pyridoxal 5-Phosphate, and Calcium L-5-Methyltetrahydrofolate at $20 per serving. This makes it an excellent choice for consumers seeking the benefits of active B vitamins without the higher price tag of the Life Extension original, ensuring efficient nutrient absorption.
85 Value
Hi Potency B Complex
Natural Factors
4.7
★★★★★
(13054 ratings)
At $12 per serving, Natural Factors Hi Potency B Complex offers a strong value by providing a comprehensive 'B50' dose from a reputable brand. While it may not feature all the active forms found in the Life Extension product, it delivers a solid and effective B-complex for daily needs at a significantly more accessible price, balancing quality and affordability.
98 Performance
Two-Per-Day Capsules
Life Extension
4.7
★★★★★
(85932 ratings)
This is a superior alternative because it is a comprehensive multivitamin from the same reputable brand, Life Extension, offering an even broader spectrum of nutrients beyond just B vitamins. It maintains the high quality and active forms of B vitamins found in the original product while adding essential minerals, antioxidants, and other beneficial compounds for more holistic health support.
97 Performance
Advanced Nutrients
Thorne
4.6
★★★★★
(851 ratings)
Thorne is a highly respected brand known for its exceptional purity and use of highly bioavailable nutrient forms. This multivitamin provides active B vitamins (e.g., Methylcobalamin, Pyridoxal 5-Phosphate, Riboflavin 5'-Phosphate Sodium, Folate as Methylfolate) at clinically relevant dosages, combined with a robust array of other high-quality vitamins and minerals, making it a step up for those seeking premium, comprehensive nutritional support.
100 Performance
Life Extension Mix Capsules
Life Extension
4.7
★★★★★
(492 ratings)
Representing the pinnacle of multi-nutrient supplementation, Life Extension Mix is the brand's most advanced formula, offering exceptionally high potencies and the most bioavailable forms of all vitamins, including an even more robust B-complex profile than the original. It includes a vast array of specialized nutrients, botanicals, and antioxidants, providing unmatched comprehensive support for overall health and longevity.