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Melatonin 3 mg

Natrol
4.6
★ ★ ★ ★ ★
(7369 ratings)
Melatonin 3 mg
Product Image
Score78
An affordable 3 mg tablet is practical for sleep onset, but B6 and calcium add little and there is no overnight-release support.
How scoring works
Quantity:60 Tablet(s) • (60 servings)
Goals:
Sleep Support

Score 78

An affordable 3 mg tablet is practical for sleep onset, but B6 and calcium add little and there is no overnight-release support.
How scoring works
$7.79($0.12 per serving)
Amazon
$ 7.79
Vitacost
$ 8.35
iHerb
$ 7.79
Walmart
$ 8.96
Pure Formulas
$ 9.73
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Analysis

The 3 mg serving may suit adults who need more than a low-dose tablet for bedtime timing. A single tablet and extensive consumer use support practical routine use.

Vitamin B6 reaches 10 mg and calcium 63 mg, but neither meaningfully improves melatonin's sleep-onset mechanism. No time-release feature is stated.

Serving cost is low and all active amounts are clear. Users taking other B6 supplements should consider the added daily amount even though melatonin remains the main active.

Who is it for
  • Adults seeking moderate-dose melatonin
  • People focused on falling asleep
  • Users comfortable with added B6
Best for
  • Bedtime sleep timing
  • Low-cost routine use
  • Users who prefer tablets

Pros

  • Clear 3 mg amount
  • Low serving cost
  • Large consumer-use history
  • Lists all active amounts

Cons

  • No time-release feature
  • B6 offers limited direct sleep value
  • Calcium contribution is minor
  • May be more than sensitive users need

Warnings

  • Melatonin may cause next-day drowsiness
  • Count the 10 mg vitamin B6 amount if combining multiple B6-containing supplements

Nutrient quality

83 Highest impact

A standard tablet may start more slowly and lacks overnight release. The melatonin amount fits a practical sleep-support range.

Ingredient transparency

78 High impact

The melatonin and any listed supporting nutrients have specific amounts. The provided facts omit the complete inactive-ingredient and flavoring list.

Customer satisfaction

71 High impact

The supplied aggregate rating is strong. No specific review comments are provided to assess whether negative complaints repeat.

Value for money

79 High impact

The formula quality is reasonable for its simple sleep-support role. The low recurring cost provides good serving value.

Report analysis

Goals

Sleep Support
Impact
Highest effect
A+ Goal FitA- Strength of SupportC CoverageA Formula Quality
Melatonin · 3 mg

Melatonin supports sleep timing and can help with sleep onset. The 3 mg amount is well suited with a lower-dose sleep-signaling approach.

The standard tablet may start more slowly and lacks overnight-release support. Vitamin B6 and calcium add little direct sleep coverage.

Study evidence
Melatonin Supportive 181 studies
Vitamin B6 Disputed 7 studies

Ingredients

IngredientAmount per serving
Vitamin B6 (Pyridoxine Hydrochloride)
10 mg
Calcium (Calcium Carbonate)
63 mg
Melatonin
3 mg
Adults 18–50 Dairy Free Children 4+ Vegetarian
Report overview
Melatonin · 3 mg OverallScore65
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA- Value

The standard format may start more slowly and offers no stated overnight-release support. The dose aligns well with physiological sleep signaling. The serving cost is close to the market median and offers good value.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Meta-analysis: melatonin for the treatment of primary sleep disorders.
    Ferracioli-Oda E; Qawasmi A; Bloch MH · PloS one · 2013
    Meta-analysis1,683 participants19 studies pooledSleep Support forMelatonin
  2. Efficacy on sleep parameters and tolerability of melatonin in individuals with sleep or mental disorders: A systematic review and meta-analysis.
    Salanitro M; Wrigley T; Ghabra H; de Haan E; Hill CM; Solmi M; Cortese S · Neuroscience and biobehavioral reviews · 2022
    Meta-analysis1,998 participants34 studies pooledSleep Support forMelatonin
  3. Exogenous melatonin as a treatment for secondary sleep disorders: A systematic review and meta-analysis.
    Li T; Jiang S; Han M; Yang Z; Lv J; Deng C; Reiter RJ; Yang Y · Frontiers in neuroendocrinology · 2019
    Meta-analysis205 participants7 studies pooledSleep Support forMelatonin
  4. Efficacy of melatonin with behavioural sleep-wake scheduling for delayed sleep-wake phase disorder: A double-blind, randomised clinical trial.
    Sletten TL; Magee M; Murray JM; Gordon CJ; Lovato N; Kennaway DJ; Gwini SM; Bartlett DJ; Lockley SW; Lack LC; Grunstein RR; Rajaratnam SMW; Delayed Sleep on Melatonin (DelSoM) Study Group · PLoS medicine · 2019
    Randomized trial116 participantsSleep Support forMelatonin
  5. Melatonin treatment for age-related insomnia.
    Zhdanova IV; Wurtman RJ; Regan MM; Taylor JA; Shi JP; Leclair OU · The Journal of clinical endocrinology and metabolism · 2001
    Randomized trial30 participantsSleep Support forMelatonin
  6. Effects of melatonin on postoperative sleep quality: a systematic review, meta-analysis, and trial sequential analysis.
    Tsukinaga A; Mihara T; Takeshima T; Tomita M; Goto T · Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023
    Meta-analysis516 participants8 studies pooledSleep Support forMelatonin
  7. Unintended consequences: college students' melatonin usage, sleep disturbance, and depressive symptoms.
    Peltz JS; Rogge R · Sleep and biological rhythms · 2025
    Cohort study331 participantsSleep Support forMelatonin
  8. The Effectiveness of Melatonin for Sleep Disturbances in Parkinson' Disease: Systematic Review and Meta-Analysis.
    Yousef O; Abouelmagd ME; Khaddam H; Shbani A; Yousef R; Meshref M; Hanafi I · Journal of sleep research · 2026
    Meta-analysis409 participants8 studies pooledSleep Support forMelatonin
  9. Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety.
    Wade AG; Ford I; Crawford G; McConnachie A; Nir T; Laudon M; Zisapel N · BMC medicine · 2010
    Randomized trial791 participantsSleep Support forMelatonin
  10. Effects of exogenous melatonin on sleep: a meta-analysis.
    Brzezinski A; Vangel MG; Wurtman RJ; Norrie G; Zhdanova I; Ben-Shushan A; Ford I · Sleep medicine reviews · 2005
    Meta-analysis284 participants8 studies pooledSleep Support forMelatonin
  11. Efficacy of vitamins B1 and B6 as an adjunctive therapy to lithium in bipolar-I disorder: A double-blind, randomized, placebo-controlled, clinical trial.
    Zandifar A; Mousavi S; Schmidt NB; Badrfam R; Seif E; Qorbani M; Mehrabani Natanzi M · Journal of affective disorders · 2023
    Randomized trial66 participantsSleep Support forVitamin B6
  12. Therapeutic effects of magnesium and vitamin B6 in alleviating the symptoms of restless legs syndrome: a randomized controlled clinical trial.
    Jadidi A; Rezaei Ashtiani A; Khanmohamadi Hezaveh A; Aghaepour SM · BMC complementary medicine and therapies · 2023
    Randomized trial75 participantsSleep Support forVitamin B6
  13. Effects of poly-gamma-glutamic acid and vitamin B6 supplements on sleep status: a randomized intervention study.
    García-García C; Baik I · Nutrition research and practice · 2022
    Randomized trial47 participantsSleep Support forVitamin B6
  14. Effects of Vitamin B6 (Pyridoxine) and a B Complex Preparation on Dreaming and Sleep.
    Adventure-Heart DJ; Madden NA; Delfabbro P · Perceptual and motor skills · 2018
    Randomized trial100 participantsSleep Support forVitamin B6
  15. The effect of pyridoxine administration on melatonin secretion in normal men.
    Luboshitzky R; Ophir U; Nave R; Epstein R; Shen-Orr Z; Herer P · Neuro endocrinology letters · 2003
    Randomized trial12 participantsSleep Support forVitamin B6