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New MOOD

Onnit
4.3
★ ★ ★ ★ ★
(775 ratings)
5-HTP 150 mg
Tryptophan 400 mg
Product Image
Score86

Premium dual-precursor (5-HTP + Tryptophan) mood formula with a tranquil botanical blend and bioavailable magnesium.

How scoring works
Quantity:60 Capsule(s) • (30 servings)
Goals:
Stress Relief
Weight Loss
Mood Support
Sleep Support

Score 86

Premium dual-precursor (5-HTP + Tryptophan) mood formula with a tranquil botanical blend and bioavailable magnesium.

How scoring works

Also available as

1 option
30 servings 5-HTP 150 mg, Tryptophan 400 mg • 30 Capsule(s) • 15 servings $23.99 ($1.59 per serving)
$56.93($1.89 per serving)
Vitacost
$ 56.93
iHerb
$ 59.90
iHerb
$ 59.90
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Analysis

High-potency 150 mg of 5-HTP is paired with 400 mg of L-tryptophan to support neurotransmitter levels from two different angles. A proprietary tranquility blend of botanicals like lemon balm and valerian adds extra support for mental calm.

Magnesium bisglycinate chelate is included in its highly bioavailable form to aid physical relaxation and stress resilience. Standardized extracts and meaningful vitamin cofactors reflect a premium investment in emotional balance.

Liquid capsule delivery ensures a straightforward experience, though the cost per serving is higher than many competitors. This multi-layered strategy targets both immediate relaxation and the long-term building blocks for mood.

Who is it for
  • Users seeking a premium mood stack
  • Individuals wanting dual serotonin precursors
  • People looking for high-quality mineral forms
Best for
  • Comprehensive mood support
  • Managing intense stress
  • Evening mental relaxation

Pros

  • Dual precursors (5-HTP + L-Tryptophan)
  • Includes highly bioavailable Magnesium Bisglycinate
  • Diverse botanical tranquility blend
  • Professional-grade formulation

Cons

  • Higher price per serving
  • Proprietary blend hides individual herb doses
  • Requires multiple capsules per serving

Warnings

  • Monitor for daytime sleepiness
  • Not to be combined with prescription antidepressants

Nutrient quality

96 Highest impact

High-strength serving of dual serotonin precursors is supported by highly bioavailable mineral and vitamin cofactors. This combination ensures robust support for neurotransmitter synthesis and emotional resilience.

Ingredient transparency

86 Highest impact

Labeling clearly identifies the amounts of most active ingredients, though the proprietary tranquility blend obscures the specific doses of individual herbs. Detailed identification of nutrient forms ensuring consumer clarity regarding the formula's quality.

Customer satisfaction

90 Highest impact

Solid average ratings and a healthy review base indicate a reliable user experience for comprehensive mood support. Feedback confirms the effectiveness of the multi-precursor approach for navigating daily stress.

Value for money

69 High impact

Premium pricing reflects the use of high-quality nutrient forms and a comprehensive multi-mechanism approach. While expensive per serving, it offers significant value for individuals seeking robust and multifaceted support.

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Goals

Stress Relief
Impact
Highest effect
A Goal FitA Strength of SupportA CoverageA Formula Quality

A potent blend of 5-HTP and L-Tryptophan provides a concentrated approach to supporting the body's natural serotonin production. Meaningfully dosed magnesium bisglycinate and vitamin B6 are included as essential cofactors to enhance the metabolic pathway for mood regulation.

A specialized tranquility blend of botanical extracts further supports a balanced nervous system and emotional resilience. This multi-mechanism formula is designed for those seeking comprehensive daily support for navigating psychological pressure.

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Weight Loss
Impact
Highest effect
A- Goal FitA- Strength of SupportA- CoverageA+ Formula Quality

5-HTP is combined with L-Tryptophan, Magnesium, Vitamin B6, and a botanical blend including Lemon Balm and Chamomile to support relaxation and satiety. This formulation provides 150 mg of 5-HTP to help manage appetite signals and curb cravings.

Increased serotonin availability via multiple precursors supports feelings of fullness, while the tranquil botanicals help manage stress-induced eating. This multi-angled approach addresses both satiety and the emotional stressors that can derail weight management efforts.

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Mood Support
Impact
Highest effect
A+ Goal FitB Strength of SupportA CoverageA- Formula Quality

Utilizing high-strength servings of 5-Hydroxytryptophan and L-tryptophan supports a robust supply of precursors for serotonin production. This dual-precursor approach is augmented by vitamin B6 and magnesium, which serve as necessary cofactors for neurotransmitter synthesis and nervous system health.

Incorporating a 'Tranquility Blend' of various botanicals adds further adaptogenic-like support for stress management. While the total ingredient profile is comprehensive, the use of a proprietary blend for the botanical components limits transparency regarding the specific dosage of each herb.

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Sleep Support
Impact
Highest effect
A- Goal FitA- Strength of SupportA- CoverageA- Formula Quality

Combining high doses of tryptophan and 5-HTP provides comprehensive support for the body's natural synthesis of serotonin and melatonin. Magnesium bisglycinate chelate further aids relaxation by supporting the nervous system and muscle function during rest.

Multi-pathway approach includes a blend of botanicals like valerian and chamomile to manage evening stress levels. Transparent labeling of the primary amino acid components ensures the efficacy of these concentrated ingredients can be verified.

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Ingredients

IngredientAmount per serving
Vitamin D (Vitamin D3)
 25 mcg
Niacin (Inositol Hexanicotinate)
 30 mg
Vitamin B6 (Pyridoxine Hydrochloride)
 20 mg
Magnesium (Magnesium Bisglycinate Chelate)
 40 mg
Onnit Tranquility Blend
450 mg
L-Tryptophan
400 mg
5-Hydroxytryptophan
150 mg
Gluten Free Adults 18–50
Report overview
5-HTP · 150 mg OverallScore60
C- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyF Value
A robust blend of 150mg 5-HTP, tryptophan, and botanical extracts is formulated to support a balanced mood. The capsules contain a variety of supportive nutrients like magnesium and vitamin B6.
View ingredientView products
Tryptophan · 400 mg OverallScore48
D+ Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyF Value
Capsule-based options such as these integrate tryptophan with supportive nutrients and are highly regarded by consumers for supporting emotional well-being. Inclusion of 5-HTP and vitamins provides a broad strategy for those looking to support their natural neurotransmitter levels.
View ingredientView products
96 Value

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5-HTP 200mg

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L-Tryptophan 500 mg

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4.6
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5-HTP 200 mg

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L-Tryptophan 500 mg

Doctor's Best
4.5
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93 Performance

5-HTP 200 mg Time Release

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4.5
★★★★★
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Using time-release technology ensures that the 200 mg dose of 5-HTP is delivered gradually to help maintain steady neurotransmitter levels throughout the day. This specialized format may also support better digestive tolerance compared to immediate-release capsules.
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5-HTP 50 mg

NOW
4.7
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(14464 ratings)
Offering a gentle 50 mg dose of 5-HTP derived from Griffonia simplicifolia, these capsules provide a highly affordable way to support serotonin levels. This format is ideal for individuals seeking a lower maintenance dose rather than high-potency servings.
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5-HTP 100 mg

Doctor's Best
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(13254 ratings)
Delivering 100 mg of standardized 5-HTP at a low price per serving allows for cost-effective mood and sleep support. This straightforward mono-ingredient approach provides high flexibility for individuals managing their specific amino acid intake.
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L-Tryptophan 1000 mg

AN Amazing Nutrition Amazing Formulas
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★★★★★
(2676 ratings)
Providing a clinical-strength 1000 mg dose of L-tryptophan supports robust serotonin synthesis and nighttime relaxation. This high milligram density tablet offers exceptional value for individuals requiring significant precursor support.
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96 Value

5-HTP Enhanced with Vitamins B6 and C

Doctor's Best
4.8
★★★★★
(10291 ratings)
Combining 100 mg of 5-HTP with vitamins B6 and C provides the necessary cofactors for optimized neurotransmitter synthesis. This synergistic blend offers comprehensive support for mood and relaxation at an efficient price point.
Other sellers (4)
95 Value

5-HTP 200mg

Best Naturals
4.8
★★★★★
(270 ratings)
Delivering a high-potency 200 mg dose of Griffonia-sourced 5-HTP supports the body's natural production of serotonin for sleep and mood. It provides a more concentrated serving than the original for individuals with robust neurotransmitter needs.
Other sellers (2)
94 Value

L-Tryptophan 500 mg

Advanced Nutrition by Zahler
4.6
★★★★★
(140 ratings)
Integrating L-tryptophan with vitamin B3 supports metabolic pathways that prioritize serotonin synthesis in the brain. This focused approach ensures the amino acid is used effectively for emotional balance rather than other metabolic needs.
Other sellers (2)
95 Performance

5-HTP 200 mg

NutraBio
4.7
★★★★★
(771 ratings)
Pairing 200 mg of 5-HTP with 50 mg of vitamin B6 supports the efficient enzymatic conversion into active serotonin. This high-potency combination provides the essential cofactor needed for optimal neurotransmitter production and emotional stability.
Other sellers (1)
95 Performance

L-Tryptophan 500 mg

Doctor's Best
4.5
★★★★★
(2149 ratings)
Utilizing pharmaceutical-grade TryptoPure ensures a highly refined source of this essential amino acid for neurological support. This standardized L-tryptophan supports emotional stability and healthy sleep cycles with consistent bioactivity.
Other sellers (3)
93 Performance

5-HTP 200 mg Time Release

Natrol
4.5
★★★★★
(8016 ratings)
Using time-release technology ensures that the 200 mg dose of 5-HTP is delivered gradually to help maintain steady neurotransmitter levels throughout the day. This specialized format may also support better digestive tolerance compared to immediate-release capsules.
Other sellers (4)
Report alternatives