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Ortho Sleep

AOR Advanced Orthomolecular Research Advanced
4.3
(471 ratings)
Theanine 200 mg
GABA 100 mg
5-HTP 100 mg
Melatonin 3 mg
Valerian 150 mg
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Score91

Multi-layered professional sleep aid combining hormones, aminos, and herbs for comprehensive nighttime support.

How scoring works
Quantity:60 Capsule(s)(30 servings)
Goals:
Sleep Support
Stress Relief
Mood Support
Weight Loss
Brain Health
Productivity Boost
Cognitive Support

Score 91

Multi-layered professional sleep aid combining hormones, aminos, and herbs for comprehensive nighttime support.

How scoring works
$34.89($1.16 per serving)
Pure Formulas
$ 35.17
Amazon
$ 34.89
iHerb
$ 35.16
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Analysis

L-theanine, valerian, and lemon balm are paired with melatonin to support a quieted mental state before bed. Passionflower and GABA further contribute to reducing the time it takes to fall asleep naturally.

Meaningful 100 mg dose of 5-HTP supports the synthesis of key neurotransmitters essential for rest. Standardized extracts ensure that every serving provides a consistent level of botanical activity.

Premium investment in this formula offers significant functional depth for those with persistent sleep needs. The use of capsules ensures a straightforward and clean experience for the user.

Who is it for
  • Users needing intensive sleep support
  • People seeking a multi-pathway nighttime blend
  • Individuals looking for high-standard extracts
Best for
  • Reducing sleep latency
  • Deep mental relaxation
  • Comprehensive sleep architecture

Pros

  • Addresses virtually all sleep pathways
  • Includes 3 mg of Melatonin
  • Standardized botanicals for quality
  • Highly pure ingredients

Cons

  • Higher price per serving
  • Contains many ingredients which may increase sensitivity
  • Melatonin dose might cause grogginess in some

Warnings

  • Do not drive after taking
  • Monitor for morning drowsiness

Nutrient quality

96 Highest impact

Selection of diverse amino acids, hormones, and botanicals provides exceptionally broad coverage of sleep-regulating pathways. Meaningful doses of L-theanine and 5-HTP ensure functional support for nighttime relaxation.

Ingredient transparency

98 Highest impact

Labeling is highly transparent, providing specific milligram amounts for every active component without the use of hidden proprietary blends. Detailed naming of extracts ensuring consumer clarity regarding ingredient sources and forms.

Customer satisfaction

88 Highest impact

Solid average ratings and a sufficient review base indicate a reliable user experience for intensive sleep support. Feedback confirms the effectiveness of the multi-ingredient blend for reducing sleep latency and improving rest quality.

Value for money

79 High impact

Premium pricing reflects the exceptionally comprehensive and high-quality nature of the formulation. While expensive per serving, it offers significantly more complexity than basic melatonin or 5-HTP products.

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Goals

Impact
Highest effect
A+ Goal FitA Strength of SupportA+ CoverageA+ Formula Quality

A highly comprehensive blend of lemon balm, valerian, theanine, and melatonin addresses virtually every major pathway involved in rest. This formula includes 5-HTP and GABA to support neurotransmitter balance and physical relaxation before bedtime.

By combining hormonal support with several calming botanical extracts, it provides a multi-faceted approach to reducing sleep latency. These ingredients appear exceptionally well aligned for individuals seeking intensive support for a restful night.

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Impact
Highest effect
A Goal FitA- Strength of SupportA CoverageA Formula Quality

A comprehensive multi-pathway blend integrates amino acids, botanical extracts, and hormones to support relaxation and nighttime rest. Meaningfully dosed L-Theanine and 5-HTP are combined with GABA and valerian to address different mechanisms of the stress response.

Low-dose melatonin assists in resetting the sleep-wake cycle, which is often disrupted by chronic pressure. The transparent labeling allows for precise tracking of each active component's contribution to emotional resilience.

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Impact
Highest effect
A Goal FitB+ Strength of SupportA CoverageA Formula Quality

This multi-nutrient blend pairs serotonin precursors with relaxation-promoting botanicals to support a balanced mood and healthy sleep patterns. Multiple biological pathways are addressed through a combination of amino acids, hormones, and herbal extracts.

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Impact
Highest effect
B Goal FitA- Strength of SupportA CoverageA+ Formula Quality

5-HTP is combined with Melatonin, GABA, L-Theanine, and calming botanicals to support healthy sleep and manage stress-induced eating. This multi-ingredient formula provides 100 mg of 5-HTP, which helps manage hunger signals via serotonin support.

While the primary focus is on rest, the inclusion of ingredients that lower stress and support satiety may contribute to long-term weight management success. Addressing high cortisol and poor sleep quality is an important indirect factor in healthy body composition.

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Impact
High effect
B Goal FitB Strength of SupportB- CoverageA- Formula Quality

Lemon Balm, L-Theanine, and Melatonin are included to support the restoration phases of cognitive health through improved sleep quality. High-quality rest is essential for clearing metabolic waste and consolidating daily memories.

Valerian and Passionflower further assist in managing mental fatigue by encouraging a healthy transition into sleep. Each ingredient appears well aligned with the neurological downtime required to maintain executive function and mental clarity.

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Impact
High effect
C Goal FitB+ Strength of SupportD+ CoverageC- Formula Quality

L-Theanine and Lemon Balm are featured in this selection to support a state of calm, which may help manage stress during task transitions. The inclusion of B-vitamins and amino acids like 5-HTP contributes to the foundational support of neurotransmitter synthesis.

The formula primarily addresses relaxation and sleep through the addition of Melatonin and Valerian root. While these ingredients are effective for recovery, the sedating properties may limit their utility for active focus and mental clarity during demanding working hours.

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Ingredients

IngredientAmount per serving
Lemon Balm (Melissa officinalis L.) aerial parts extract
300 mg
L-Theanine
200 mg
Valerian (Valeriana officinalis L.) root extract
150 mg
GABA
100 mg
L-5-Hydroxytryptophan (Griffonia)
100 mg
Passionflower (Passiflora incarnata L.) aerial parts extract
32 mg
Melatonin
3 mg
Gluten Free Adults 18–50 Vegan Dairy Free Women Vegetarian
Report overview
Theanine · 200 mg OverallScore88
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value
Sleep-focused blend provides a significant 200mg dose of the primary amino acid alongside Valerian and Melatonin. Comprehensive approach incorporates several botanical extracts and hormones known for their calming characteristics.
GABA · 100 mg OverallScore70
B- Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyD- Value
Ortho Sleep focuses on sleep maintenance by pairing GABA with melatonin and relaxing herbs like lemon balm. Such combinations are often utilized to support a restful night and healthy sleep patterns. Multiple botanical extracts work together to complement the primary active ingredients.
5-HTP (Griffonia) · 100 mg OverallScore66
C+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value
Premium sleep support blend provides 100mg of 5-HTP alongside melatonin, GABA, and calming botanicals. This multi-ingredient formula appears well aligned for comprehensive nighttime support in a capsule format.
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