Product Image

Therapeutic-M

21st Century
4.8
★ ★ ★ ★ ★
(644 ratings)
Iodine 150 mcg
Molybdenum 75 mcg
Manganese 2 mg
Copper 2 mg
Zinc 15 mg
Chloride 8 mg
Iron 9 mg
Product Image
Score79
A low-cost broad multivitamin with useful iodine and iron, but basic forms and light major minerals limit quality.
How scoring works
Quantity:130 Tablet(s) • (130 servings)
Goals:
Immunity
General Health

Score 79

A low-cost broad multivitamin with useful iodine and iron, but basic forms and light major minerals limit quality.
How scoring works
$9.99($0.07 per serving)
iHerb
$ 9.99
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Analysis

One tablet supplies a broad set of vitamins and trace minerals, including vitamin D3, iodine, iron, zinc, selenium, copper, and manganese. The 130-serving bottle is convenient for inexpensive routine coverage.

Magnesium, zinc, and copper rely on oxide forms, while folate, B12, and several other vitamins use standard forms. Silicon is only 2 mg as silicon dioxide and does not provide meaningful hair or nail focus.

The formula fits adults who specifically need a low-cost multi with 9 mg iron. It is less suitable for users seeking substantial calcium, magnesium, potassium, or specialized structural support.

Who is it for
  • Adults seeking inexpensive broad coverage
  • Users whose plan includes 9 mg supplemental iron
  • People wanting one-tablet convenience
Best for
  • Basic daily multivitamin use
  • General and immune support
  • Iodine and trace-mineral coverage

Pros

  • One-tablet serving
  • 130 servings
  • Broad vitamin and mineral list
  • 150 mcg iodine

Cons

  • Several oxide mineral forms
  • Low calcium, magnesium, and potassium
  • Only 2 mg silicon dioxide
  • Uses standard folate and B12 forms

Warnings

  • Vitamin K can interfere with warfarin dosing
  • The 9 mg iron serving may be unsuitable for iron-overload disorders or people advised to avoid supplemental iron
  • Preformed vitamin A from acetate requires pregnancy caution

Nutrient quality

73 High impact

The formula offers partial support but has a dose or purpose-alignment limitation. Form uncertainty or weak secondary amounts reduce confidence in its practical contribution.

Ingredient transparency

85 Highest impact

The listed active ingredients have specific amounts and no proprietary blend hides the core doses. Full use directions and a complete inactive-ingredient list are not supplied.

Customer satisfaction

69 High impact

The aggregate satisfaction signal is strong and the supplied volume is moderate. No specific experience details are supplied to assess repeated complaints or purpose-related outcomes.

Value for money

86 Highest impact

The serving provides favorable value for the disclosed core actives. Minor form or targeting limitations keep the category comparison from being fully settled.

Report analysis

Goals

Immunity
Immunity
Impact
High effect
A- Goal FitC+ Strength of SupportB+ CoverageB Formula Quality
Magnesium · 100 mgVitamin C · 90 mgZinc · 15 mgVitamin A · 1500 mcgVitamin D · 10 mcgSelenium · 70 mcg

Vitamin A, vitamin C, vitamin D, zinc, selenium, and iron address several immune pathways. The multivitamin is broad and nutritional rather than focused on short-term immune support.

Zinc reaches maintenance level, while vitamin C, vitamin D, selenium, and iron are modest for targeted use. Several inorganic mineral forms and duplicate source listings reduce form quality and formula clarity.

Study evidence
Iron Supportive 23 studies
Selenium Mixed 37 studies
Vitamin A Supportive 107 studies
Vitamin C Supportive 53 studies
Vitamin D Supportive 85 studies
Zinc Supportive 73 studies
General Health
General Health
Impact
High effect
A Goal FitC Strength of SupportB+ CoverageB- Formula Quality
Folate · 667 mcg DFEVitamin B12 · 12 mcgVitamin D · 10 mcgMagnesium · 100 mgVitamin K · 28 mcgBoron · 150 mcgSelenium · 70 mcgZinc · 15 mgVitamin C · 90 mg

The wide vitamin and mineral profile can help cover several common nutritional gaps and supports core metabolic, immune, and antioxidant functions. Its breadth is a clear strength for general wellness.

Most amounts are transparent, but magnesium oxide, zinc oxide, cupric oxide, and sodium selenate are less favorable forms. The formula also includes several very small trace additions whose practical contribution is uncertain.

Study evidence
Magnesium Supportive 114 studies
Zinc Supportive 60 studies
Detoxification
Detoxification
Impact
Moderate effect
C- Goal FitC Strength of SupportC CoverageB- Formula Quality
Folate · 667 mcg DFEVitamin B12 · 12 mcgVitamin B6 · 6 mgMolybdenum · 75 mcgSelenium · 70 mcgMagnesium · 100 mgVitamin E · 27 mgZinc · 15 mgVitamin C · 90 mgRiboflavin · 3.4 mg

Molybdenum, selenium, zinc, folate, vitamin C, and B vitamins support several normal metabolic pathways. The product remains a therapeutic multivitamin and lacks a focused glutathione, biliary, or liver-protection active.

All amounts are visible, but zinc oxide and several standard vitamin forms limit quality. The formula is most relevant when correcting a nutrient gap rather than as a broad detoxification product.

Study evidence
Folate Supportive 16 studies
Molybdenum Adverse 1 study
Selenium Supportive 10 studies
Vitamin C Supportive 9 studies
Zinc Supportive 30 studies
Metabolism Boost
Metabolic Hormone BalanceMetabolic B-Vitamins
Metabolism Boost
Impact
Moderate effect
C- Goal FitD+ Strength of SupportC CoverageB Formula Quality
Biotin · 30 mcgNiacin · 20 mgVitamin B12 · 12 mcgRiboflavin · 3.4 mgThiamin · 3 mgVitamin B5 · 10 mgVitamin B6 · 6 mgVitamin D · 10 mcgZinc · 15 mgMagnesium · 100 mg

Iodine and selenium provide direct nutritional support for thyroid hormone production and metabolism. B vitamins add general cellular energy support without acting as stimulants.

Iodine reaches a practical daily amount, while selenium and magnesium remain modest. Chromium is present below a targeted supplemental level and uses a basic chloride form.

Study evidence
Chromium Supportive 47 studies
Iodine Mixed 17 studies
Magnesium Supportive 61 studies
Selenium Mixed 28 studies
Bone Health
Healthy Bone RemodelingBone Mineral Preservation
Bone Health
Impact
Moderate effect
B- Goal FitD Strength of SupportC+ CoverageC- Formula Quality
Phosphorus · 35 mgVitamin K · 28 mcgMagnesium · 100 mgCalcium · 145 mgVitamin D · 10 mcgCopper · 2 mgManganese · 2 mgBoron · 150 mcgZinc · 15 mgVitamin C · 90 mg

A broad set of minerals plus vitamin D3 and vitamin K1 touches most major bone-health mechanisms. Low amounts of several specialty minerals and basic forms make much of that coverage shallow.

Calcium, magnesium, and vitamin D provide only partial daily support. Oxide minerals, vitamin K1, trace boron, and poorly absorbed silicon keep the extensive ingredient list from becoming a strong bone formula.

Study evidence
Boron Supportive 5 studies
Calcium Supportive 144 studies
Magnesium Supportive 48 studies
Silicon Supportive 13 studies
Vitamin D Supportive 202 studies
Energy
Energy
Impact
Moderate effect
C+ Goal FitF Strength of SupportD CoverageB+ Formula Quality
Iodine · 150 mcgVitamin D · 10 mcgVitamin B5 · 10 mgMagnesium · 100 mgRiboflavin · 3.4 mgThiamin · 3 mgVitamin B12 · 12 mcgIron · 9 mgPotassium · 11 mg

B vitamins, iron, iodine, and magnesium provide basic support for metabolic energy production. Vitamin B12 is very low, magnesium uses oxide, and no ingredient directly supports alertness or stress resilience.

Coverage is confined to basic nutrient metabolism and possible correction of iron deficiency. The conventional multivitamin is coherent but offers no focused energy strategy.

Study evidence
Iodine Adverse 3 studies
Iron Supportive 74 studies
Magnesium Supportive 4 studies
Hair Health
Hair Health
Impact
Moderate effect
C- Goal FitD- Strength of SupportC- CoverageD+ Formula Quality
Biotin · 30 mcgVitamin D · 10 mcgZinc · 15 mgIron · 9 mgVitamin C · 90 mg

Iron, iodine, zinc, vitamin D3, folate, and B12 provide basic support for nutritional and thyroid-related shedding. Vitamin C usefully complements the iron contribution.

Iron is modest, while copper oxide and silicon dioxide provide weak form quality and little structural support. The broad therapeutic multivitamin is therefore more suitable for maintenance than targeted hair growth or strengthening.

Study evidence
Copper Adverse 4 studies
Folate Mixed 15 studies
Iodine No effect 1 study
Iron Disputed 25 studies
Silicon Supportive 2 studies
Vitamin C Mixed 5 studies
Zinc Supportive 22 studies

Ingredients

IngredientAmount per serving
Vitamin A (Beta-Carotene, Vitamin A Acetate)
 1500 mcg
Vitamin C (Ascorbic Acid)
 90 mg
Vitamin D3 (Cholecalciferol)
 10 mcg
Vitamin E (DL-Alpha-Tocopheryl Acetate)
 27 mg
Vitamin K (Phytonadione)
 28 mcg
Thiamine (Thiamine Hydrochloride)
 3 mg
Riboflavin (Vitamin B2)
 3.4 mg
Niacin (Niacinamide)
 20 mg
Vitamin B6 (Pyridoxine Hydrochloride)
 6 mg
Folate
667 mcg DFE
Vitamin B12 (Cyanocobalamin)
 12 mcg
Biotin
30 mcg
Pantothenic Acid (D-Calcium Pantothenate)
 10 mg
Calcium (Calcium Carbonate, Dicalcium Phosphate)
 145 mg
Iron (Ferrous Fumarate)
 9 mg
Phosphorus (Dicalcium Phosphate)
 35 mg
Iodine (Potassium Iodide)
 150 mcg
Magnesium (Magnesium Oxide)
 100 mg
Zinc (Zinc Oxide)
 15 mg
Selenium (Sodium Selenate)
 70 mcg
Copper (Cupric Oxide)
 2 mg
Manganese (Manganese Sulfate)
 2 mg
Chromium (Chromium Chloride)
 50 mcg
Molybdenum (Sodium Molybdate)
 75 mcg
Chloride (Potassium Chloride, Vitamin B6)
 8 mg
Potassium (Potassium Chloride, Potassium Iodide)
 11 mg
Boron (Sodium Borate)
 150 mcg
Tin (Stannous Chloride)
 10 mcg
Silicon (Silicon Dioxide)
 2 mg
Vanadium (Sodium Metavanadate)
 10 mcg
Gluten Free Adults 18–50
Report overview
Iodine (Potassium Iodide) · 150 mcg OverallScore99
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

Potassium iodide provides a stable, water-soluble iodine form with reliable absorption. The 150 mcg amount falls in the optimal daily-support range and is explicitly disclosed. The serving is very economical for the iodine amount delivered.

View ingredientView products
Molybdenum (Sodium Molybdate) · 75 mcg OverallScore74
C- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB+ Value

Sodium molybdate offers a soluble form with good absorption potential, while the 75 mcg dose reaches the effective target. The disclosed amount remains well below the adult upper limit. The low serving cost gives the effective dose good practical value.

View ingredientView products
Manganese (Manganese Sulfate) · 2 mg OverallScore70
D- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyA+ Value

The sulfate form limits absorption quality despite clear identification. The clearly disclosed 2 mg amount supports nutritional maintenance but falls short of the target range for bone-matrix support. The very low serving cost provides strong budget value despite the basic form.

View ingredientView products
Loading alternative details
80 Performance

Baby & Me 2 Postnatal Multi

MegaFood
<p>Methylfolate, methylcobalamin, active riboflavin, chelated minerals, choline, iron, and vitamin D3 offer a clear form upgrade. The formula is designed for postnatal use, so its iron and iodine profile is not a general-purpose replacement for everyone.</p>
82 Performance

M.V. Teen

Futurebiotics
<p>Practical vitamin and trace-mineral amounts provide broad coverage with fewer clearly excessive doses. The teen-specific design and modest calcium and magnesium mean it should be chosen only when age and nutritional needs fit.</p>
79 Performance

Ladies' One

Bluebonnet
<p>Active B vitamins and chelated minerals improve nutrient forms while maintaining broad daily coverage and iron. Proprietary blends reduce full transparency, and the women-focused profile should match the intended user.</p>
78 Budget

Multi with Iron Century Formula

Swanson
<p>Broad vitamin and mineral coverage is retained at a slightly lower serving cost. Basic nutrient forms remain, and the higher iron amount is appropriate only for people with a demonstrated need.</p>
80 Budget

One Daily Maximum

21st Century
<p>Wide vitamin and mineral coverage comes in a very inexpensive daily tablet. Several inorganic mineral forms and token trace additions limit quality, but the lower cost suits basic nutritional maintenance.</p>
80 Budget

Sentry Adults

21st Century
<p>A similarly broad one-tablet nutrient profile costs less per serving and includes useful iron, iodine, vitamin D3, and B vitamins. Oxide, sulfate, and carbonate minerals keep form quality close to the original rather than improving it.</p>
79 Value

Daily Vits

NOW
<p>Core vitamins, iron, calcium, and zinc provide broad daily coverage at a still-low serving cost. Vitamin D2 and uncertain totals for repeated entries limit the upgrade, but the balance remains practical for basic use.</p>
75 Value

Alive! Women's Energy Complete Multivitamin

Nature's Way
<p>A broad vitamin and mineral profile covers common daily needs with practical serving value. Several basic mineral forms remain, though the women-focused formula provides a more tailored alternative when iron is appropriate.</p>
84 Value

Complete Multivitamin

Bayer One A Day Men's
<p>Broad maintenance amounts and full active-dose disclosure offer strong value with no iron. Most chemical forms remain unspecified, but the formula may fit men who do not need supplemental iron.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effect of oral intake of choline-stabilized orthosilicic acid on skin, nails and hair in women with photodamaged skin.
    Barel A; Calomme M; Timchenko A; De Paepe K; Demeester N; Rogiers V; Clarys P; Vanden Berghe D · Archives of dermatological research · 2006
    Randomized trial50 participantsHair Health Nail Health forSilicon
  2. Nail Supplements: When, How, and Why?
    Zaraa I; Richert B · Skin appendage disorders · 2026
    Narrative reviewNail Health forSilicon
  3. [Comparative study of the urinary excretion of boron, calcium, magnesium and phosphorus in postmenopausal women with and without osteoporosis].
    José Ramón V; Mora Mora M; Marino Alarcón O; Hernández G; Josefina Linares L; Urdaneta Romero H; Arévalo González E · Investigacion clinica · 2013
    Case-control study45 participantsBone Health forBoron
  4. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women.
    Nielsen FH; Hunt CD; Mullen LM; Hunt JR · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 1987
    Single-arm trial12 participantsBone Health forBoron
  5. The relationship between boron and magnesium status and bone mineral density in the human: a review.
    Volpe SL; Taper LJ; Meacham S · Magnesium research · 1994
    Narrative reviewBone Health forBoron
  6. Effects of boron supplementation on bone mineral density and dietary, blood, and urinary calcium, phosphorus, magnesium, and boron in female athletes.
    Meacham SL; Taper LJ; Volpe SL · Environmental health perspectives · 1995
    Randomized trial28 participantsBone Health forBoron
  7. Metabolic responses of postmenopausal women to supplemental dietary boron and aluminum during usual and low magnesium intake: boron, calcium, and magnesium absorption and retention and blood mineral concentrations
    C D Hunt, J L Herbel, F H Nielsen · The American Journal of Clinical Nutrition · 1997
    Non-randomized trial11 participantsBone Health forBoron
  8. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  9. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  10. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  11. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  12. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  13. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  14. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  15. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  16. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  17. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  18. The effect of choline-stabilized orthosilicic acid in patients with peri-implantitis: an exploratory randomized, double-blind, placebo controlled study.
    Teughels W; Celik GU; Tarce M; De Cock I; Persyn SM; Haytac MC · BMC oral health · 2021
    Randomized trial21 participantsBone Health forSilicon
  19. Calcium Phosphate Modified with Silicon vs. Bovine Hydroxyapatite for Alveolar Ridge Preservation: Densitometric Evaluation, Morphological Changes and Histomorphometric Study.
    Cadenas-Vacas G; Martínez-Rodríguez N; Barona-Dorado C; Sánchez-Labrador L; Cortés-Bretón Brinkmann J; Meniz-García C; Martínez-González JM · Materials (Basel, Switzerland) · 2021
    Non-randomized trialBone Health forSilicon
  20. Silicon: a review of its potential role in the prevention and treatment of postmenopausal osteoporosis.
    Price CT; Koval KJ; Langford JR · International journal of endocrinology · 2013
    Narrative reviewBone Health forSilicon
  21. Osteogenic Effect of a Bioactive Calcium Alkali Phosphate Bone Substitute in Humans.
    Knabe C; Adel-Khattab D; Rezk M; Cheng J; Berger G; Gildenhaar R; Wilbig J; Günster J; Rack A; Heiland M; Knauf T; Stiller M · Bioengineering (Basel, Switzerland) · 2023
    Clinical trial38 participantsBone Health forSilicon
  22. Silicon and bone health.
    Jugdaohsingh R · The journal of nutrition, health & aging · 2007
    Narrative reviewBone Health forSilicon
  23. Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
    Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
    Randomized trial454 participantsBone Health forVitamin D
  24. Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
    Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
    Narrative reviewBone Health forVitamin D
  25. Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
    Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
    Meta-analysis1,786 participants20 studies pooledBone Health forVitamin D
  26. Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
    Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Randomized trial193 participantsBone Health forVitamin D
  27. Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
    Rasool N; Munir Y · European journal of clinical nutrition · 2026
    Randomized trial612 participantsBone Health forVitamin D
  28. Comparison of efficacy of folic acid and silymarin in the management of antiepileptic drug induced liver injury: a randomized clinical trial.
    Asgarshirazi M; Shariat M; Sheikh M · Hepatobiliary & pancreatic diseases international : HBPD INT · 2018
    Randomized trial55 participantsDetoxification forFolate
  29. Homocysteine, folate, and nonalcoholic fatty liver disease: a systematic review with meta-analysis and Mendelian randomization investigation.
    Yuan S; Chen J; Dan L; Xie Y; Sun Y; Li X; Larsson SC · The American journal of clinical nutrition · 2022
    Meta-analysis30,368 participants22 studies pooledDetoxification forFolate
  30. Serum folate levels and urinary arsenic methylation profiles in the US population: NHANES, 2003-2012.
    Zhang X; Xu X; Zhong Y; Power MC; Taylor BD; Carrillo G · Journal of exposure science & environmental epidemiology · 2020
    Cross-sectional study11,016 participantsDetoxification forFolate
  31. Association between serum folate levels and blood concentrations of cadmium and lead in US adults.
    Wu Z; Hu H; Wang C; Wu J; Xiong Y; Fu Y; Cheng X; Su H; Li P · Environmental science and pollution research international · 2022
    Cross-sectional study15,501 participantsDetoxification forFolate
  32. Effects of Folic Acid Supplementation on Liver Enzymes, Lipid Profile, and Insulin Resistance in Patients with Non-Alcoholic Fatty Liver Disease: A Randomized Controlled Trial.
    Molaqanbari MR; Zarringol S; Talari HR; Taghizadeh M; Bahmani F; Mohtashamian A; Ebrahimzadeh A; Sharifi N · Advanced biomedical research · 2023
    Randomized trial66 participantsDetoxification forFolate
  33. Human molybdenum exposure risk in industrial regions of China: New critical effect indicators and reference dose.
    Kuang HX; Li MY; Zeng XW; Chen D; Zhou Y; Zheng T; Xiang MD; Wu QZ; Chen XC; Dong GH; Yu YJ · Ecotoxicology and environmental safety · 2024
    Cross-sectional study2,267 participantsDetoxification forMolybdenum
  34. Supplementation with selenium can influence nausea, fatigue, physical, renal, and liver function of children and adolescents with cancer.
    Vieira ML; Fonseca FL; Costa LG; Beltrame RL; Chaves CM; Cartum J; Alves SI; Azzalis LA; Junqueira VB; Pereria EC; Rocha KC · Journal of medicinal food · 2015
    Randomized trialDetoxification forSelenium
  35. [Selenium and oxidative stress in cancer patients].
    Gorozhanskaia ÉG; Sviridova SP; Dobrovol'skaia MM; Zybrikhina GN; Kashnia ShR · Biomeditsinskaia khimiia · 2014
    Single-arm trial40 participantsDetoxification forSelenium
  36. Comprehensive Insights into the Health Effects of Selenium Exposure and Supplementation Among the Chinese Community Middle-Aged and Elderly: a Combined Retrospective Cohort Study and Intervention Study.
    Li C; Peng X; Zheng J; Shi K; Qin L; Yang Q; Wang Z; Liu Y; Huang L · Biological trace element research · 2024
    Other40 participantsDetoxification forSelenium
  37. Heavy metals and metalloids exposure and liver function in Chinese adults - A nationally representative cross-sectional study.
    Wang S; Lyu Y; Ji S; Liu N; Wu B; Zhao F; Li Z; Qu Y; Zhu Y; Xie L; Li Y; Zhang Z; Song H; Hu X; Qiu Y; Zheng X; Zhang W; Yang Y; Li F; Cai J; Zhu Y; Cao Z; Tan F; Shi X · Environmental research · 2024
    Cross-sectional study9,445 participantsDetoxification forSelenium
  38. Selenium-Biofortified Strawberries Improve Glucose Homeostasis and Hepatic Function: A 30-Day Randomized Controlled Trial in Healthy Adults.
    Vasto S; Di Rosa L; Ferrantelli V; Fiore AS; Giordano CP; Cannizzaro A; Sabatino L; Macaluso A; Caldarella R; Caldara GF; Baldassano S · Nutrients · 2026
    Randomized trial35 participantsDetoxification forSelenium
  39. Vitamin C supplementation ameliorates liver function profile and antiviral treatment response in Hepatitis C patients.
    Nayila I; Javed MS; Khan MA; Hussain G; Raza Naqvi SA; Ali S; Jabeen Z; Shahnawaz S; Akram R; Iman T; Hassan Dogar MZ; Malik SA · Pakistan journal of pharmaceutical sciences · 2022
    Non-randomized trial200 participantsDetoxification forVitamin C
  40. Effect of ascorbic acid-rich diet on in vivo-induced oxidative stress.
    Alleva R; Di Donato F; Strafella E; Staffolani S; Nocchi L; Borghi B; Pignotti E; Santarelli L; Tomasetti M · The British journal of nutrition · 2012
    Non-randomized trial46 participantsDetoxification forVitamin C
  41. Dietary Vitamin C Intake Is Associated With Improved Liver Function and Glucose Metabolism in Chinese Adults.
    Luo X; Zhang W; He Z; Yang H; Gao J; Wu P; Ma ZF · Frontiers in nutrition · 2022
    Observational study8,307 participantsDetoxification forVitamin C
  42. Plasma ascorbate deficiency is associated with impaired reduction of sulfamethoxazole-nitroso in HIV infection.
    Trepanier LA; Yoder AR; Bajad S; Beckwith MD; Bellehumeur JL; Graziano FM · Journal of acquired immune deficiency syndromes (1999) · 2005
    Observational studyDetoxification forVitamin C
  43. Roles of endogenous ascorbate and glutathione in the cellular reduction and cytotoxicity of sulfamethoxazole-nitroso.
    Lavergne SN; Kurian JR; Bajad SU; Maki JE; Yoder AR; Guzinski MV; Graziano FM; Trepanier LA · Toxicology · 2006
    Clinical trial53 participantsDetoxification forVitamin C
  44. [Therapy of Wilson disease].
    Smolarek C; Stremmel W · Zeitschrift fur Gastroenterologie · 1999
    Narrative reviewDetoxification forZinc
  45. Efficacy of Zinc Supplement in Minimal hepatic Encephalopathy: A prospective, Randomized Controlled Study (Zinc-MHE Trial).
    Janyajirawong R; Vilaichone RK; Sethasine S · Asian Pacific journal of cancer prevention : APJCP · 2021
    Randomized trial69 participantsDetoxification forZinc
  46. Effect of zinc on liver cirrhosis with hyperammonemia: a preliminary randomized, placebo-controlled double-blind trial.
    Katayama K; Saito M; Kawaguchi T; Endo R; Sawara K; Nishiguchi S; Kato A; Kohgo H; Suzuki K; Sakaida I; Ueno Y; Habu D; Ito T; Moriwaki H; Suzuki K · Nutrition (Burbank, Los Angeles County, Calif.) · 2015
    Randomized trial18 participantsDetoxification forZinc
  47. Effects of low dose zinc supplementation on biochemical markers in non-alcoholic cirrhosis: a randomized clinical trial.
    Somi MH; Rezaeifar P; Ostad Rahimi A; Moshrefi B · Archives of Iranian medicine · 2012
    Randomized trial60 participantsDetoxification forZinc
  48. Correlation of Serum Zinc Levels with Hepatic Encephalopathy Severity in Patients with Decompensated Liver Cirrhosis: A Prospective Observational Study from Egypt.
    Semeya AA; Elgamal R; Othman AAA · Biological trace element research · 2025
    Observational study200 participantsDetoxification forZinc
  49. Association of radioactive iodine treatment with survivorship symptoms and primary care utilisation in women of reproductive age with thyroid cancer: a retrospective cohort study.
    Devanarayan P; Hartman M; Partin M · Family medicine and community health · 2026
    Cohort study10,882 participantsEnergy forIodine
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  65. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
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  66. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
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    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
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  68. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
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  69. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
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    Bhat YJ; Manzoor S; Khan AR; Qayoom S · Indian journal of dermatology, venereology and leprology · 2009
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    Millington KR; Marsh JM · International journal of cosmetic science · 2021
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  74. Preserving fibre health: reducing oxidative stress throughout the life of the hair fibre.
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    Zhang W; Fan M; Wang C; Mahawar K; Parmar C; Chen W; Yang W; Global Bariatric Research Collaborative · Obesity surgery · 2021
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  76. Quantitative Analysis of Selected Circulating Hematological Biomarkers, Essential Minerals, Vitamins, and Thyroid Hormones in Females Affected by Hair Loss.
    Al-Fawaeir S; Al-Odat I · Diseases (Basel, Switzerland) · 2025
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  77. Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer.
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  79. Phase I-II study of vinorelbine in combination with 5-fluorouracil and folinic acid as first-line chemotherapy in metastatic breast cancer: a regimen with a low subjective toxic burden.
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    El Fékih N; Kamoun H; Fazaa B; El Ati J; Zouari B; Kamoun MR; Gaigi S · Revue medicale de Liege · 2010
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  81. The Association Between Alopecia Areata and Iron Deficiency Anemia: A Large-Scale Population-Based Case-Control Study.
    Davidovici B; Drutin Y; Ben-Tov A; Mimouni D; Wohl Y · Journal of personalized medicine · 2026
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  82. Iron Deficiency and Nonscarring Alopecia in Women: Systematic Review and Meta-Analysis.
    Treister-Goltzman Y; Yarza S; Peleg R · Skin appendage disorders · 2022
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  83. Comparative Analysis of Postoperative Hair Loss and Micronutrient Deficiencies After One-Anastomosis Gastric Bypass Versus Sleeve Gastrectomy.
    Chinisaz F; Maleki T; Najjari K; Miratashi Yazdi SA · Obesity surgery · 2026
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  84. Assessment of Serum Ferritin Levels in Female Patients With Telogen Effluvium.
    Thamotharan N; Harikumar MV; Sundaram M; Swaminathan A; Rangarajan S · Cureus · 2026
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  85. Diagnosis and treatment of female alopecia: Focusing on the iron deficiency-related alopecia.
    Lin CS; Chan LY; Wang JH; Chang CH · Tzu chi medical journal · 2023
    Cohort study155 participantsHair Health forIron
  86. Effect of oral intake of choline-stabilized orthosilicic acid on hair tensile strength and morphology in women with fine hair
    R R Wickett, E Kossmann, A Barel, N Demeester, P Clarys, D Vanden Berghe, M Calomme · Archives of Dermatological Research · 2007
    Randomized trial48 participantsHair Health forSilicon
  87. Management of hair loss associated with endocrine therapy in patients with breast cancer: an overview.
    Karatas F; Sahin S; Sever AR; Altundag K · SpringerPlus · 2016
    Narrative reviewHair Health forVitamin C
  88. Elucidating causal relationships of diet-derived circulating antioxidants and the risk of non-scarring alopecia: A Mendelian randomization study.
    Ba Y; Shen L; Peng X; Zhang Y; Wang J · Medicine · 2024
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  89. Alterations of plasma antioxidants and mitochondrial DNA mutation in hair follicles of smokers.
    Liu CS; Chen HW; Lii CK; Tsai CS; Kuo CL; Wei YH · Environmental and molecular mutagenesis · 2002
    Observational studyHair Health forVitamin C
  90. Removal of synthetic hair dye using formamidine sulfinic acid and other sulfinate precursors.
    Hawkes JA; Lewis DM; Mama J; Murray J · International journal of cosmetic science · 2026
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  91. A Zinc Sulphate-Resistant Acrodermatitis Enteropathica Patient with a Novel Mutation in SLC39A4 Gene.
    Kilic M; Taskesen M; Coskun T; Gürakan F; Tokatli A; Sivri HS; Dursun A; Schmitt S; Küry S · JIMD reports · 2013
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  92. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  93. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
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    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
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    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
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    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
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    Mu Q; Chen L; Gao X; Shen S; Sheng W; Min J; Wang F · Science bulletin · 2023
    Narrative reviewImmunity forIron
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    Ganz T · Current topics in microbiology and immunology · 2006
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    Preston AE; Drakesmith H; Frost JN · Immunotherapy advances · 2025
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    Barber MF; Elde NC · Trends in genetics : TIG · 2016
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    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
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    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
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    Coutsoudis A; Broughton M; Coovadia HM · The American journal of clinical nutrition · 1991
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  141. Magnesium Supplementation and the Effects on Wound Healing and Metabolic Status in Patients with Diabetic Foot Ulcer: a Randomized, Double-Blind, Placebo-Controlled Trial.
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  144. The Effects of Selenium Supplementation on Gene Expression Related to Insulin and Lipid Metabolism, and Pregnancy Outcomes in Patients with Gestational Diabetes Mellitus: a Randomized, Double-Blind, Placebo-Controlled Trial.
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    Randomized trial36 participantsMetabolism Boost forSelenium
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    Niu X; Zhang Y; Liu Y; Zhu Y; Fang B; Hu C; Xu X; Wang R; Sang Y; Zhang Q; Guo J · Frontiers in nutrition · 2026
    Randomized trial58 participantsMetabolism Boost forSelenium